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pentobarbital will decrease the extent or effect of atazanavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.pentobarbital will lessen the extent or influence of midostaurin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Potent CYP3A4 inducers could reduce mido